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Search Results for " tumor-related protein "

Targets

5

Compounds

4

Natural Products

46

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T3623 Cobimetinib RG7420,XL518,GDC-0973 Apoptosis , MEK
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e...
T10406 Tuvusertib M1774,ATR inhibitor 1 Apoptosis , ATM/ATR , Others , Chk
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks...
T9533 BC-LI-0186 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide Others
BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...
TQ0141 Taltobulin HTI-286,SPA-110 Apoptosis , Microtubule Associated
Taltobulin (HTI-286) is a synthetic analog of the tripeptide cysteine, a microtubule protein inhibitor that inhibits liver tumor cell proliferation in vitro and tumor growth in vivo.Taltobulin is cytotoxic, induces mitot...
T26981 Ceralasertib formate Ceralasertib,AZD-6738,AZD 6738,AZD6738
Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine prot...
Cat No. Product Name Synonyms Targets
TN1410 Asperulosidic acid ASPA ERK , NF-κB
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...
T3314 Perillyl alcohol Isocarveol,Perilla alcohol Apoptosis , Endogenous Metabolite
Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-...
T6S1315 Oroxylin A 6-Methoxybaicalein,Baicalein 6-methyl ether Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...
T81484 Phorbol 12-tiglate
Phorbol 12-tiglate, a derivative of Phorbol, which in turn is a hydrolyzed product of Croton oil, plays a role in tumor promotion through activation of protein kinase C. This compound and its related derivatives are empl...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00564 PLXDC2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mouse Plexin domain-containing protein 2(PLXDC2) is a single-pass type I membrane protein. The protein is expressed in tumor endothelium and in vessels of some normal tissues, such as the muscle and lung. PLXDC2 can inte...
TMPH-02599 C1QTNF6 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
C1QTNF6 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02600 C1QL3 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in a...
TMPH-02555 C1QL1 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
TMPJ-01304 C1QTNF1 Protein, Human, Recombinant (His) Human HEK293 Cells
C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-termin...
TMPJ-00981 PTX3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory...
TMPH-01129 C1QTNF3 Protein, Human, Recombinant (His) Human E. coli
C1QTNF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02598 C1QTNF3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
C1QTNF3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is Q9ES30.
TMPH-01130 C1QTNF3 Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
C1QTNF3 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPJ-00110 GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The p...
TMPH-02497 Adipolin Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Adipolin Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8R2Z0.
TMPH-02496 Adipolin Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Adipolin Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q8R2Z0.
TMPJ-01372 Cornulin Protein, Human, Recombinant (His) Human E. coli
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-ter...
TMPJ-00546 EFNA1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPJ-00274 LTBR Protein, Human, Recombinant (His) Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,...
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa and the accession number is P29965.
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant Human E. coli
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian) Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is 23-28 KDa and the accession number is P29965.
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain) Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPH-01048 CEACAM5 Protein, Human, Recombinant (E398K, His) Human HEK293 Cells
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion mo...
TMPK-00248 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL...
TMPK-00134 ULBP-1 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00135 ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00249 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL...
TMPJ-00999 UBE2D1 Protein, Human, Recombinant (GST) Human E. coli
Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes...
TMPY-02572 TXNDC17 Protein, Human, Recombinant Human E. coli
Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein fa...
TMPY-01416 OLFM4 Protein, Human, Recombinant (His) Human HEK293 Cells
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit va...
TMPJ-01412 LRP-12 Protein, Human, Recombinant (His) Human HEK293 Cells
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 c...
TMPJ-00680 ANGPTL7 Protein, Human, Recombinant (His) Human HEK293 Cells
Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain....
TMPJ-00578 CEACAM21 Protein, Human, Recombinant (His) Human HEK293 Cells
Carcinoembryonic antigen-related cell adhesion molecule 21 is a protein that in humans is encoded by the CEACAM21 gene. It belongs to the immunoglobulin superfamily. CEA family.containing 1 Ig-like C2-type (immunoglobuli...
TMPY-02651 P63 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar f...
TMPY-01816 Pentraxin 3 Protein, Human, Recombinant (His) Human HEK293 Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin dom...
TMPY-04547 PBK/TOPK Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the chara...
TMPY-02759 Kallikrein 6/KLK6 Protein, Human, Recombinant (His) Human HEK293 Cells
KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence...
TMPY-02084 Thioredoxin 2/TRX2 Protein, Human, Recombinant (His) Human E. coli
Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanot...
TMPY-04936 BCL2A1 Protein, Human, Recombinant (His) Human E. coli
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in...
TMPY-02440 SAP/SH2D1A Protein, Human, Recombinant (His) Human E. coli
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TMPY-02712 Serpin B3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPY-01771 Latexin Protein, Mouse, Recombinant (His) Mouse E. coli
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly express...
TMPY-01204 SMYD2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
SET and MYND domain-containing protein 2, also known as HSKM-B, SMYD2, and KMT3C, is a member of the SMYD protein family. It contains one MYND-type zinc finger and one SET domain. Not much is known about SMYD2. However, ...
TMPY-02516 Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as ...
TMPY-04260 P38 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TMPY-00918 SFRP1 Protein, Human, Recombinant (His) Human HEK293 Cells
Secreted frizzled-related protein 1, also known as sFRP1, is a 35 kDa prototypical member of the SFRP family. SFRP family consists of five secreted glycoproteins in humans acting as extracellular signaling ligands. Each ...
TMPY-00564 MCP-4 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family ...
PLXDC2 Protein, Mouse, Recombinant (His)
TMPJ-00564
Species: Mouse
Expression System: HEK293 Cells
C1QTNF6 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02599
Species: Mouse
Expression System: E. coli
C1QL3 Protein, Mouse, Recombinant (His & Myc)
TMPH-02600
Species: Mouse
Expression System: Baculovirus Insect Cells
C1QL1 Protein, Mouse, Recombinant (His)
TMPH-02555
Species: Mouse
Expression System: P. pastoris (Yeast)
C1QTNF1 Protein, Human, Recombinant (His)
TMPJ-01304
Species: Human
Expression System: HEK293 Cells
PTX3 Protein, Mouse, Recombinant (His)
TMPJ-00981
Species: Mouse
Expression System: HEK293 Cells
C1QTNF3 Protein, Human, Recombinant (His)
TMPH-01129
Species: Human
Expression System: E. coli
C1QTNF3 Protein, Mouse, Recombinant (His)
TMPH-02598
Species: Mouse
Expression System: HEK293 Cells
C1QTNF3 Protein, Human, Recombinant (His & Myc)
TMPH-01130
Species: Human
Expression System: Baculovirus Insect Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00110
Species: Mouse
Expression System: HEK293 Cells
Adipolin Protein, Mouse, Recombinant (His)
TMPH-02497
Species: Mouse
Expression System: Baculovirus Insect Cells
Adipolin Protein, Mouse, Recombinant (E. coli, His)
TMPH-02496
Species: Mouse
Expression System: E. coli
Cornulin Protein, Human, Recombinant (His)
TMPJ-01372
Species: Human
Expression System: E. coli
EFNA1 Protein, Human, Recombinant (hFc)
TMPJ-00546
Species: Human
Expression System: HEK293 Cells
LTBR Protein, Human, Recombinant (His)
TMPJ-00274
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag)
TMPJ-00153
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant
TMPJ-00151
Species: Human
Expression System: E. coli
CD40 Ligand Protein, Human, Recombinant (Mammalian)
TMPJ-00150
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00152
Species: Human
Expression System: HEK293 Cells
MMP-12 Protein, Human, Recombinant (catalytic domain)
TMPY-02869
Species: Human
Expression System: E. coli
C-ABL/ABL1 Protein, Human, Recombinant (GST)
TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CEACAM5 Protein, Human, Recombinant (E398K, His)
TMPH-01048
Species: Human
Expression System: HEK293 Cells
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
TMPK-00248
Species: Human
Expression System: HEK293 Cells
ULBP-1 Protein, Human, Recombinant (His & Avi)
TMPK-00134
Species: Human
Expression System: HEK293 Cells
ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00135
Species: Human
Expression System: HEK293 Cells
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00249
Species: Human
Expression System: HEK293 Cells
UBE2D1 Protein, Human, Recombinant (GST)
TMPJ-00999
Species: Human
Expression System: E. coli
TXNDC17 Protein, Human, Recombinant
TMPY-02572
Species: Human
Expression System: E. coli
OLFM4 Protein, Human, Recombinant (His)
TMPY-01416
Species: Human
Expression System: HEK293 Cells
LRP-12 Protein, Human, Recombinant (His)
TMPJ-01412
Species: Human
Expression System: HEK293 Cells
ANGPTL7 Protein, Human, Recombinant (His)
TMPJ-00680
Species: Human
Expression System: HEK293 Cells
CEACAM21 Protein, Human, Recombinant (His)
TMPJ-00578
Species: Human
Expression System: HEK293 Cells
p63 Protein, Human, Recombinant (His & GST)
TMPY-02651
Species: Human
Expression System: Baculovirus Insect Cells
Pentraxin 3 Protein, Human, Recombinant (His)
TMPY-01816
Species: Human
Expression System: HEK293 Cells
PBK/TOPK Protein, Human, Recombinant (His)
TMPY-04547
Species: Human
Expression System: Baculovirus Insect Cells
Kallikrein 6/KLK6 Protein, Human, Recombinant (His)
TMPY-02759
Species: Human
Expression System: HEK293 Cells
Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)
TMPY-02084
Species: Human
Expression System: E. coli
BCL2A1 Protein, Human, Recombinant (His)
TMPY-04936
Species: Human
Expression System: E. coli
SAP/SH2D1A Protein, Human, Recombinant (His)
TMPY-02440
Species: Human
Expression System: E. coli
Serpin B3 Protein, Human, Recombinant (His)
TMPY-02712
Species: Human
Expression System: Baculovirus Insect Cells
Latexin Protein, Mouse, Recombinant (His)
TMPY-01771
Species: Mouse
Expression System: E. coli
SMYD2 Protein, Human, Recombinant (His)
TMPY-01204
Species: Human
Expression System: Baculovirus Insect Cells
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
TMPY-02516
Species: Human
Expression System: HEK293 Cells
p38 Protein, Human, Recombinant (His)
TMPY-04260
Species: Human
Expression System: Baculovirus Insect Cells
SFRP1 Protein, Human, Recombinant (His)
TMPY-00918
Species: Human
Expression System: HEK293 Cells
MCP-4 Protein, Human, Recombinant (His)
TMPY-00564
Species: Human
Expression System: P. pastoris (Yeast)
Cat No. Product Name
L2200 Tyrosine Kinase Inhibitor Library

1016 compounds
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L1300 PI3K-AKT-mTOR Compound Library

420 compounds
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
TargetMol